Welcome to the Shoichet Lab
"Our research program requires a cross disciplinary approach where aspects of engineering, chemistry, and biology are applied to the fields of Regenerative Medicine, Tissue Engineering and Drug Delivery. We approach unsolved problems in medicine by creating a series of design criteria which we then use to formulate solutions."
Ontario Chief Scientist Dr. @MollyShoichet & her team (@ShoichetLab @UofT) are engineering new materials to help restore vision to people who lose their sight from diseases like age-related #maculardegeneration. Just 1 of the amazing ways #WeAreOntarioInnovation pic.twitter.com/KXaLSe1f3t
— OntarioInnovation (@OntInnovation) April 19, 2018
The Numbers
Features
AmacaThera
Globe and Mail - U of T startup raises $10.3 million to develop post-surgery pain treatment. Globe and Mail
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Chemical Institute of Canada Medal
Congratulations to Professor Shoichet who has been named the 2021 recipient of the Chemical Institute of Canada (CIC) Medal. Chemical Institute of CanadaUniversity of Toronto, Chemical Engineering & Applied Chemistry News
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Feature of the Month
We would like to welcome Dr. Adam Forman, a post-doctoral fellow, to our lab. We would also like to congratulate Dr. Laura Smith on securing a job at AmacaThera through a MITACs PDF with our lab.
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Gerhard Herzberg Canada Gold Medal for Science and Engineering
Congratulations to Professor Molly Shoichet on receiving Gerhard Herzberg Canada Gold Medal, Canada’s highest honour for science and engineering research. Natural Sciences and Engineering Research Council of CanadaCBC NewsCBC Quirks and QuarksCBC RadioGlobe and MailResearch MoneyUniversity of Toronto Engineering NewsUofT Celebrates
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Recent Publications
Publication
“Wielding the double-edged sword of inflammation: building biomaterial-based strategies for immunomodulation in ischemic stroke treatment” Letko Khait, N.; Ho, E.; Shoichet, M.S. 2021 Advanced Functional Materials, special issue on Advanced Materials for Drug Delivery and Theranostics. 2010674: 1-32; doi: 10.1002/adfm.202010674 Publication
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Publication
“Photochemically-activated notch signaling hydrogel preferentially differentiates human derived hepatoblasts to cholangiocytes” Rizwan M; Fokina A; Kivijärvi T; Ogawa M; Kufleitner M; Laselva O; Smith LJ; Bear CE; Ogawa S; Keller G; Shoichet MS. 2020 , Advanced Functional Materials, 2006116; doi: 10.1002/adfm.202006116 Publication
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Publication
“Re-engineering Biocatalysts: Computational Redesign of Chondroitinase ABC Improves Efficacy and Stability” Hettiaratchi MH; O’Meara MJ; O’Meara TR; Pickering AJ; Letko-Khait N; Shoichet MS. 2020 , Science Advances, 6: eabc6378; doi: 10.1126/sciadv.abc6378 Publication
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Publication
“Hydrogel-mediated co-transplantation of retinal pigmented epithelium and photoreceptors restores vision in an animal model of advanced retinal degeneration” Mitrousis, N.; Hacibekiroglu, S.; Ho, M.T.; Sauvé, Y.; Nagy, A.; van der Kooy, D.; Shoichet, M.S. 2020 Biomaterials, 257: 120233; doi: 10.1016/j.biomaterials.2020.120233 Publication
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