Welcome to the Shoichet Lab
"Our research program requires a cross disciplinary approach where aspects of engineering, chemistry, and biology are applied to the fields of Regenerative Medicine, Tissue Engineering and Drug Delivery. We approach unsolved problems in medicine by creating a series of design criteria which we then use to formulate solutions."
Ontario Chief Scientist Dr. @MollyShoichet & her team (@ShoichetLab @UofT) are engineering new materials to help restore vision to people who lose their sight from diseases like age-related #maculardegeneration. Just 1 of the amazing ways #WeAreOntarioInnovation pic.twitter.com/KXaLSe1f3t
— OntarioInnovation (@OntInnovation) April 19, 2018
The Numbers
Features
Feature of the Month: June 2019
Congratulations to Dr. Ahil Ganesh, featured among the top 25 poster presentations at the GRC on Preclinical Form and Formulation for Drug Discovery.
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International Union of Pure and Applied Chemistry
On February 7, 2019, the International Union of Pure and Applied Chemistry (IUPAC) named Dr. Molly Shoichet a 2019 Distinguished Woman in Chemistry or Chemical Engineering. International Union of Pure and Applied Chemistry Chemical Engineering News Chemistry and Industry (April 2019)
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University Affairs
The February 1, 2019 issue of University Affairs, features Dr. Molly Shoichet. Undeterred from any losses that may come her way, one constant goal that pushes Dr. Shoichet forward is to be a champion of science.
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AmacaThera
AmacaThera, a Toronto-based company commercializing hydrogel-based drug delivery platforms, has raised $3.25 million CAD in seed financing from Sprout BioVentures, Viva Biotech, and Grey Sky Venture Partners. AmacaThera’s founding technology was discovered at the University of Toronto by Dr. Molly Shoichet, a leading expert on polymer design. AmacaThera envisions their proprietary…
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Recent Publications
Publication
“Cationic block amphiphiles show anti-mitochondrial activity in multi-drug resistant breast cancer cells” Czupiel, P.P.; Delplace, V.; Shoichet, M.S. 2019. J. Controlled Release, 305: 210-19; doi: 10.1016/j.jconrel.2019.04.045 Publication
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Publication
“Colloidal drug aggregate stability in high serum conditions and pharmacokinetic consequence” Ganesh AN; Aman A; Logie J; Barthel BL; Cogan P; Al-awar RS; Koch TH; Shoichet BK; Shoichet MS. 2019 ACS Chemical Biology, 14: 751-57; doi: 10.1021/acschembio.9b00032 Publication
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Publication
“Local delivery of stabilized chondroitinase ABC degrades chondroitin sulfate proteoglycans in stroke-injured rat brains” Hettiaratchi MH; O’Meara MJ; Teal CJ; Payne SL; Pickering AJ; Shoichet MS. 2019 J.Controlled Release, 297: 14-25; doi: 10.1016/j.jconrel.2019.01.033 Publication
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Publication
“Local delivery of BDNF enables behavioural recovery and tissue repair in stroke-injured rats” Obermeyer JM; Tuladhar A; Payne SL; Ho E; Morshead CM; Shoichet MS. 2019 Tissue Engineering, Part A., in press, xx1-x13; doi: 10.1089/ten.TEA.2018.0215 Publication
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