Welcome to the Shoichet Lab
"Our research program requires a cross disciplinary approach where aspects of engineering, chemistry, and biology are applied to the fields of Regenerative Medicine, Tissue Engineering and Drug Delivery. We approach unsolved problems in medicine by creating a series of design criteria which we then use to formulate solutions."
The Numbers
FEATURES
Feature of the Month
We would like some new graduate students and postdoctoral fellows to our lab. From left to right, we have Alec Tiffany, Olivia Li, David Li, uan Yao and Sophia Lu.
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New Strategy for Delivery of Therapeutic Proteins could Help Treat Degenerative Eye Diseases
Finding treasures in the trash: with directed evolution, we find affibody binding partners that are highly specific with moderate affinity allowing simultaneous release of multiple factors. University of Toronto Engineering News
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U of T Researchers Design New Hydrogel for more Targeted Cancer Treatments
Biomimetic 3D hyaluronan hydrogel enables culture of multiple cancer cell types and unbiased in vivo results. University of Toronto News
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Canadian Institute of Health Research
Professor Molly Shoichet joins three other Donnelly Centre investigators who have won funding from the federal government to build maps of cellular function at the molecular level and explore new treatments for blindness. Donnelly News | From Bench and Beyond (Spring 2022)
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RECENT PUBLICATIONS
Publication
"Directed Evolution enables Simultaneous Controlled Release of Multiple Therapeutic Proteins from Biopolymer-based Hydrogels" Teal, C.J.; Hettiaratchi, M.H.; Ho, M.T.; Ortin-Martinez, A.; Ganesh, A.N.; Pickering, A.J.; Golinski, A.W.; Hackel, B.J.; Wallace, V.A.; Shoichet, M.S. 2022 Advanced Materials, e2202612: 1-14; doi: 10.1002/adma.202202612 Publication
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Publication
“Temporally controlled photouncaged epidermal growth factor influences cell fate in hydrogels” Lu, Y.H.; Baker, A.E.G.; Fokina, A.; Kufleitner, M.; Kivijäri, T.; Shoichet, M.S. 2022. ACS Biomaterials Science & Engineering, 8: 185-95; doi: 10.1021/acsbiomaterials.1c00941 Publication
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Publication
"Synthesis of an enzyme-mediated reversible crosslinked hydrogel for cell culture" Smith KA; Dang M; Baker AEG; Fuehrmann T; Fokina A; Shoichet MS. 2021, Biomacromolecules, 22: 5118-27; doi: 10.1021/acs.biomac.1c01086 Publication
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Publication
“Designing hydrogels for 3D cell culture using dynamic covalent crosslinking” Rizwan M; Baker AEG; Shoichet MS. 2021 Advanced Healthcare Materials, special issue on "Advances in Biomaterials in the last decade", 2100234: 1-23; doi: 10.1002/adhm.202100234 Publication
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