Papers: 2010 – 2019


281. Baker AEG; Bahlmann LC; Tam RY; Liu JC; Ganesh AN; Mitrousis N; Marcellus R; Spears M; Bartlett MS; Cescon DW; Bader GD; Shoichet MS. 2019 “Benchmarking to the gold standard: hyaluronan-oxime hydrogels recapitulate xenograft models with in vitro breast cancer spheroid culture”, Advanced Materials, e1901166; doi: 10.1002/adma.201901166

280. Donders, E; Ganesh, AN; Torosyan, H; Lak, P; Shoichet, BK; Shoichet, MS. "Triggered release enhances the cytotoxicity of stable colloidal drug aggregates", ACS Chemical Biology, 14: 1507-14; doi: 10.1021/acschembio.9b00247

279. Tadjaran, K; Chan, K; Shoichet, MS; Gordon, T; Borschel, GH. “Local delivery of FK506 to injured peripheral nerve enhances axon regeneration after surgical nerve repair in rats" Acta Biomaterialia, in press, xx1-x10; doi: 10.1016/j.actbio.2019.05.058

278. Malek-Adamiana, E.; Fakhourya, J; Arnold, A.E.; Martínez-Monteroa, S.; Sleiman, H.; Shoichet, M.S.; Damha, M.J. “Effect of sugar 2’,4’-modifications on gene silencing activity of small interfering RNA duplexes”, Nucleic Acid Therapeutics, 29: 187-94; doi: 10.1089/nat.2019.0792

277. Czupiel, P.P.; Delplace, V.; Shoichet, M.S. “Cationic block amphiphiles show anti-mitochondrial activity in multi-drug resistant breast cancer cells” J. Controlled Release, 305: 210-19; doi: 10.1016/j.jconrel.2019.04.045

276. Bakooshli, M.A.; Lippmann, E.S.; Mulcahy, B.; Iyer, N.; Nguyen, C.T.; Tung, K.; Stewart, B.A.; van den Dorpel, H.; Führmann, T.; Shoichet, M.S.; Bigot, A.; Pegoraro, E.; Ahn, H.; Ginsberg, H.; Zhen, M.; Ashton, R.S.; Gilbert, P.M. 2019 “A 3D culture model of innervated human skeletal muscle enables studies of the adult neuromuscular junction”, eLife, 8:e44530; doi: 10.7554/eLife.44530.001

275. Hettiaratchi, M.H.; Shoichet, M.S. 2019 “Modulated protein delivery to engineer tissue repair”, Tissue Engineering (invited perspective), 25: 925-930; doi: 10.1089/ten.TEA.2019.0066

274. Ho, M.T.; Teal, C.J.; Shoichet, M.S. 2019 “A hyaluronan/methylcellulose-based hydrogel for local cell and biomolecule delivery to the central nervous system”, Brain Research Bulletin (invited review), 148: 46-54; doi: 10.1016/j.brainresbull.2019.03.005

273. Hettiaratchi, M.H.; O’Meara, M.J.; Teal, C.J.; Payne, S.L.; Pickering A.J.; Shoichet, M.S. 2019 “Local delivery of stabilized chondroitinase ABC degrades chondroitin sulfate proteoglycans in stroke-injured rat brains”, J. Controlled Release, 297: 14-25; doi: 10.1016/j.jconrel.2019.01.033

272. Ganesh, A.N.; Aman, A.; Logie, J.; Barthel, B.L.; Cogan, P.; Al-awar, R.S.; Koch, T.H.; Shoichet, B.K.; Shoichet, M.S. 2019 “Colloidal drug aggregate stability in high serum conditions and pharmacokinetic consequence”, ACS Chemical Biology, 14: 751-57; doi: 10.1021/acschembio.9b00032

271. Vonderwalde, I.; Azimi, A.; Rolvink, G.; Ahlfors, J.E.; Shoichet, M.S.; Morshead, C.M. “Transplantation of directly reprogrammed human neural precursor cells following stroke promotes synaptogenesis and functional recovery”, Translational Stroke Research, Feb 2019; doi: 10.1007/s12975-019-0691-x

270. Tsai, E.L.S.; Ortin-Martinez, A.; Gurdita, A.; Comanita, L.; Yan, N.; Smiley, S.; Delplace, V.; Shoichet, M.S.; Nickerson, PEB; Wallace, V. 2019 "Modeling of photoreceptor donor/host interaction following transplantation reveals a role for Crx, Müller glia and Rho/ROCK signaling in neurite outgrowth" Stem Cells, 37: 529-41; doi: 10.1002/stem.2985

269. Obermeyer, J.M.; Tuladhar, A.; Payne, S.L.; Ho, E.; Morshead, C.M.; Shoichet, M.S. 2019 “Local delivery of BDNF enables behavioural recovery and tissue repair in stroke-injured rats”, Tissue Engineering, Part A., 25: 1175-87; doi: 10.1089/ten.TEA.2018.0215

268. Bellver-Landete, V.; Bretheau, F.; Vallières, N.; Lessard, M.; Vernoux, M.E.; Fuehrmann, T.; Shoichet, M.S.; Lacroix, S. 2019 “Microglia are an essential component of the protective scar that forms after spinal cord injury” Nature Communications, 10: 1-18; doi: 10.1038/s41467-019-08446-0

267. Obermeyer, J.M.; Gracias, A.; Ho, E.; Shoichet, M.S. 2019 “Influencing neuroplasticity in stroke treatment with advanced biomaterials-based approaches”, Advanced Drug Delivery Reviews (invited review), 148: 204-18; doi: 10.1016/j.addr.2018.12.012, xx1-x15

266. Payne, S.L.; Tuladhar, A.; Obermeyer, J.M.; Varga, B.V.; Teal, C.J.; Morshead, C.M.; Nagy, A.; Shoichet, M.S. 2018 “Initial cell maturity influences transplantation success in the stroke-injured rodent brain” Biomaterials, 192: 309-22; doi:10.1016/j.biomaterials.2018.11.020

265. Delplace, V.; Ortin-Martinez, A.; Tsai, E.L.S.; Amin, A.N.; Wallace, V.; Shoichet, M.S. 2019 “Controlled release strategy designed for intravitreal protein delivery to the retina”, J. Controlled Release, 293: 10-20; doi: 10.1016/j.jconrel.2018.11.012


264. Tam, R.Y.; Yockell-Lelievre, J.; Smith LJ; Julian LM; Choey C; Baker AEG; Hasim MS; Dimitroulakos J; Stanford WL; Shoichet MS. 2018 “Rationally designed 3D hydrogels model invasive lung diseases enabling high-content drug screening”, Advanced Materials, 1806214: 1-9; doi: 10.1002/adma.201806214

263. Nori, S.; Khazaei, M.; Ahuja, C.S.; Ahlfors, J.E.; Yokota, K.; Liu, Y.; Wang, J.; Shibata, S.,;Chio, J.; Hettiaratchi, M.H.; Fuehrmann, T.; Shoichet, M.S.; Fehlings, M.G. “Human oligodendrogenic neural progenitor cells delivered with chondroitinase ABC facilitate functional repair of chronic spinal cord injury”, Stem Cell Reports, 11: 1433-48; doi: 10.1016/j.stemcr.2018.10.017

262. Mitrousis, N.; Fokina, A.; Shoichet, M.S. 2018 “Biomaterials for cell transplantation”, Nature Reviews Materials (invited review), 3: 441-56;
doi: 10.1038/s41578-018-0057-0

261. Khalili, S.; Ballios, B.G.; Belair- Hickey, J.; Donaldson, L.; Liu, J.;Coles, B.L.K.; Grisé, K.; Bader, G.; Wallace, V.; Bernier, G. Shoichet, M.S.; van der Kooy, D. “Induction of rod versus cone photoreceptor-specific progenitors from retinal precursor cells” Stem Cell Research, 33: 215-227; doi: 10.1016/j.scr.2018.11.005

260. Davoudi, S.; Chin, C.Y.; Cooke, M.C.; Tam, R.Y.; Shoichet, M.S.; Gilbert, P.M. 2018 “Muscle stem cell intramuscular delivery within hyaluronan methylcellulose improves engraftment efficiency and dispersion”, Biomaterials, 173: 34-46; doi 10.1016/j.biomaterials.2018.04.048

259. Ganesh, A.N.; Donders, E.N.; Shoichet, B.K.; Shoichet, M.S. 2018 "Colloidal aggregation: from screening nuisance to formulation nuance", Nano Today, 19: 188-200; doi: 10.1016/j.nantod.2018.02.011

258. Fisher, S.A.; Tam, R.Y.; Fokina, A.; Mahmoodi, M.M.; Distefano, M.D.; Shoichet, M.S. 2018 “Photo-immobilized EGF chemical gradients differentially impact breast cancer cell invasion and drug response in defined 3D hydrogels” Biomaterials, 178: 751-66; doi: 10.1016/j.biomaterials.2018.01.032

257. Arnold, A.E.; Malek-Adamian, E.; Lee, P.U.; Meng, A.; Martinez-Montero, S.; Petrecca, K.; Damha, M.J.; Shoichet, M.S. “Antibody-antisense oligonucleotide conjugate downregulates a key gene in glioblastoma stem cells”, Molecular Therapy - Nucleic Acids, 11: 518-27;
doi: 10.1016/j.omtn.2018.04.004

256. Tuladhar, A.; Payne S.L.; Shoichet, M.S. 2018 "Harnessing the potential of biomaterials for brain repair after stroke", Frontiers in Materials, 5: 1-25l; doi: 10.3389/fmats.2018.00014

255. Smith, J.S.; Taimoory, S.M.; Tam, R.Y.; Baker, A.E.G.; Binth Mohammad, N.; Trant, J.F.; Shoichet, M.S. 2018 “Diels-Alder click-crosslinked hydrogels with increased reactivity enable 3D cell encapsulation”, Biomacromolecules, 19: 926-35; doi: 10.1021/acs.biomac.7b01715

254. Thompson, R.E.; Pardieck, J.; Smith, L.J.; Kenny, P.; Crawford, L.; Shoichet, M.S.; Sakiyama-Elbert, S. 2018 “Effect of hyaluronic acid hydrogels containing astrocyte-derived extracellular matrix and/or V2a interneurons on histologic outcomes following spinal cord injury” Biomaterials, 162: 208-23; doi: 10.1016/j.biomaterilas.2018.02.013

253. May, Z; Kumar, R; Fuehrmann, T; Tam, RY; Vulic, K; Forero, J; Lucas-Osma, A; Fenrich, K; Assinck, P; Lee, M; Moulson, A; Shoichet, MS; Tetzlaff, W; Biernaskie, J; Fouad, K. “Adult skin-derived precursor Schwann cell grafts form growths in the injured spinal cord of Fischer rats”, Biomedical Materials, 13: 034101; doi: 10.1088/1748-605X/aa95f8. Impact Factor: 2.469

252. Führmann, T.; Anandakumaran, P.N.; Payne, S.L.; Pakulska, M.M.; Varga, B.V.; Nagy, A.; Tator, C.H.; Shoichet, M.S. 2018 “Combined delivery of chondroitinase ABC and human induced pluripotent stem cell-derived neuroepithelial cells promote tissue repair in an animal model of spinal cord injury”, Biomedical Materials, 13: 024103; doi: 10.1088/1748-605X/aa96dc

251. Payne, S.L.; Anandakumaran, P.N.; Varga, B.; Morshead, C.M.: Nagy, A.; Shoichet, M.S. 2018 “In vitro maturation of human iPS-derived neuroepithelial cells influences transplant survival in the stroke-injured rat brain”, Tissue Engineering, 24: 351-60; doi: 10.1089/ten.tea.2016.0515


250. Baker, A.E.G.; Tam, R.Y.; Shoichet, M.S. 2017 “Independently tuning the biochemical and mechanical properties of 3D hyaluronan-based hydrogels with oxime and Diels-Alder chemistry to culture breast cancer spheroids”, Biomacromolecules, 18: 4373-84; doi: 10.1021/ac.biomac.7b01422

249. Julian, L; Delaney, S; Wang, Y; Goldberg, A; Dore, C; Yockell-Lelièvre, J; Tam, RY; Giannikou, K; McMurray, F; Shoichet, MS; Harper, ME; Henske, E; Kwiatkowski, D; Darling, T; Moss, J; Kristof, A; Stanford, WL. 2017 “Human pluripotent stem cell-derived TSC2-haploinsufficient smooth muscle cells recapitulate features of Lymphangioleiomyomatosis”, Cancer Research, 77: 5491-502; doi: 10.1158/0008-5472.CAN-17-0925

248. Bahlmann, L.C.; Fokina, A.; Shoichet, M.S. 2017 "Dynamic bioengineered hydrogels as scaffolds for advanced stem cell and organoid culture", MRS Communications, 7: 472-86; doi: 10.1557/mrc.2017.72

247. Hettiaratchi, M.H.; Führmann, T.; Shoichet, M.S. 2017 "Recent Advances in Regenerative Medicine Approaches for Spinal Cord Injuries", Current Opinion in Biomedical Engineering (Invited Review), 4: 40-49; doi: 10.1016/j.cobme.2017.08.002

246. Arnold, A.E.; Czupiel, P.; Shoichet, M.S. 2017 "Engineered polymeric nanoparticles to guide the cellular internalization and trafficking of small interfering ribonucleic acids", Journal of Controlled Release (Invited Review), 259: 3-15; doi: 10.1016/j.jconrel.2017.02.019

245. Tam, R.Y.; Smith, L.J.; Shoichet, M.S. 2017 "Engineering cellular microenvironments with pPhoto- and enzymatically responsive hydrogels: toward biomimetic 3D cell culture models", Accounts of Chemical Research, 50: 703-13; doi: 10.1021/acs.accounts.6b00543

244. May, Z.; Torres-Espίn, A.; Lucas-Osma; A.M.; Batty, N.J.; Raposo, P.; Fenrich, K.K.; Stykel, M.G.; Führmann, T.; Shoichet, M.S.; Biernaskie, J.; Fouad, K. 2017 “Cyclosporine-immunosuppression does not affect survival of transplanted skin-derived precursor Schwann cells in the injured rat spinal cord”, Neuroscience Letters, 658: 67-72; doi: 10.1016/j.neulet.2017.08.045

243. Ganesh, A.N.; Logie, J.; McLaughlin, C.K.; Barthel, B.L.; Koch, T.; Shoichet, B.K.; Shoichet, M.S. 2017 “Leveraging colloidal aggregation for drug-rich nanoparticle formulations”, Molecular Pharmaceutics, 14: 1852-60; doi: 10.1021/acs.molpharmaceut.6b01015

242. Fisher SA; Baker AEG; Shoichet MS. 2017 "Designing peptide and protein modified hydrogels: selecting the optimal conjugation strategy", Journal of the American Chemical Society, 139: 7416-27; doi: 10.1021/jacs.7b00513

241. Fisher, S.A.; Baker, A.E.G.; Shoichet, M.S. 2017 “Designing peptide and protein modified hydrogels: selecting the optimal conjugation strategy”, Journal of the American Chemical Society (Invited Perspective), 139: 7416-27; doi: 10.1021/jacs.7b00513

240. Pakulska, M.M.; Tator, C.H.; Shoichet, M.S. 2017 “Local delivery of chondroitinase ABC with or without stromal cell-derived factor 1α promotes functional repair in the injured rat spinal cord”, Biomaterials, 134: 13-21; doi: 10.1016/j.biomaterials.2017.04.016

239. Führmann, T.; Anandakumaran, P.N.; Shoichet, M.S. 2017 "Combinatorial therapies after spinal cord injury: how can biomaterials help?", Advanced Healthcare Materials (Invited Review), 1601130: 1-22; doi: 10.1002/adhm.201601130

238. Ganesh, A.N.; McLaughlin, C.K.; Duan, D.; Shoichet, B.K.; Shoichet, M.S. 2017 “A new spin on antibody-drug conjugates: trastuzumab-fulvestrant colloidal drug aggregates target HER2-positive cells”, ACS Applied Materials & Interfaces, 9: 12195-202; doi: 10.1021/acsami.6b15987

237. Logie, J.; Ganesh, A.N.; Aman, A.M.; Al-awar, R.S.; Shoichet, M.S. 2017 “Preclinical evaluation of taxane-binding peptide-modified polymeric micelles loaded with docetaxel in an orthotopic breast cancer mouse model”, Biomaterials, 123: 39-47; doi: 10.1016/j.biomaterials.2017.01.026


236. Duan, D.; Torosyan, H.; Elnatan, D.; McLaughlin, C.K.; Logie, J.; Shoichet, M.S.; Agard, D; Shoichet, B.K. 2016 “Internal structure and preferential protein binding of colloidal aggregates”, ACS Chemical Biology, 12: 282-90; doi: 10.1021/acschembio.6b00791

235. Delplace, V.; Obermeyer, J.; Shoichet, M.S. 2016 “Local Affinity Release”, ACS Nano, 10: 6433-36; doi: 10.1021/acsnano.6b04308

234. Mahmoodi, M.M.; Fisher, S.A.; Tam, R.Y.; Goff, P.C.; Wissinger, J.E.; Blank, D.A.; Shoichet, M.S.; Distefano, M.D. 2016. “6-Bromo-7-hydroxy-3-methyl coumarin (mBhc) is an efficient multi-photon labile protecting group for thiol caging and three-dimensional chemical patterning”, Organic & Biomolecular Chemistry, 14: 8289-300; doi: 10.1039/c6ob01045h

233. Gomes, E.D.; Mendes, S.S.; Leite-Almeida, H.; Gimble, J.M.; Tam, R.Y.; Shoichet, M.S.; Sousa, N.; Silva, N.A.; Salgado, A.J. 2016 “Combination of a peptide-modified gellan gum hydrogel with cell therapy in a lumbar spinal cord injury animal model”, Biomaterials, 105:38-51; doi: 10.1016/j.biomaterials.2016.07.019

232. Pakulska, M.M.; Elliott Donaghue, I.; Obermeyer, J.; Tuladhar, A.; McLaughlin, C.K.; Shoichet, M.S. 2016 “Encapsulation-free controlled release: electrostatic interactions eliminate the need for protein encapsulation in PLGA nanoparticles”, Science Advances, 2, e1600519 doi:10.1126/sciadv.1600519

231. Tam, R.Y., Fisher, S.A.; Baker, A.E.G; Shoichet, M.S. 2016 “Transparent porous polysaccharide cryogels provide biochemically defined, biomimetic matrices for tunable 3D cell culture”, Chemistry of Materials, 28: 3762-70; doi: 10.1021/acs.chemmater.6b00627

230. Elliott Donaghue, I.; Tator, C.H.; Shoichet, M.S. 2016 “Local delivery of neurotrophin-3 and anti-NogoA promotes repair after spinal cord injury”, Tissue Engineering A, 22: 733-41.

229. McLaughlin, C.K.; Duan, D.; Ganesh, A.N.; Shoichet, B.K.; Shoichet, M.S. 2016 “Stable colloidal drug aggregates catch and release active enzymes”, ACS Chemical Biology, 11: 992-1000; doi: 10.1021/acschembio.5b00806

228. Mitrousis, N.; Tam, R.Y., Baker, A.E.G.; van der Kooy, D.; Shoichet, M.S. 2016 “Hyaluronic acid-based hydrogels enable rod photoreceptor survival and maturation in vitro through activation of the mTOR pathway”, Advanced Functional Materials, 26: 1975-85; doi: 10.1002/adfm.201504024

227. Pakulska, M.M.; Miersch, S.; Shoichet, M.S. 2016 “Designer protein delivery: from natural occurring to engineered affinity controlled release systems”, Science, 351: aac4750; doi: 10.1126/science.aac4750


226. Parker, J.; Mitrousis, N.; Shoichet, M.S. 2015 “Hydrogel for simultaneous tunable growth factor delivery and enhanced viability of encapsulated cells in vitro”, Biomacromolecules, 17: 476-84; doi: 10.1021/acs.biomac.5b01366

225. Führmann, T.; Tam, R.Y.; Ballarin, B.; Coles, B.; Elliott Dongahue, I.; van der Kooy, D.; Nagy, A.; Morshead, C.M.; Shoichet, M.S. 2016 “Injectable hydrogel promotes early survival of induced pluripotent stem cell-derived oligodendrocytes and attenuates long term teratoma formation in spinal cord injury model”, Biomaterials, 83: 23-36; doi: 10.1016/j.biomaterials.2015.12.032

224. Tajdaran, K.; Gordon, T.; Wood, M.D.; Shoichet, M.S.; Borschel, G.H. 2015 “A glial cell line-derived neurotrophic factor delivery system enhances nerve regeneration across acellular nerve allografts”, Acta Biomaterialia, 29: 62-70; doi: 10.1016/j.actbio.2015.10.001

223. Fisher, S.; Anandakumaran, P.; Owen, S.C.; Shoichet, M.S. 2015 “Tuning the microenvironment: click-crosslinked hyaluronic acid based hydrogels provide a platform for studying breast cancer cell invasion”, Advanced Functional Materials, 25: 7163-72; doi: 10.1002/adfm.201502778

222. Delplace, V.; Payne, S.L.; Shoichet, M.S. 2015 "Delivery strategies for treatment of age-related ocular diseases: from a biological understanding to biomaterial solutions", J. Controlled Release, 219: 652-68; doi: doi:10.1016/j.jconrel.2015.09.065

221. Livingston-Thomas, J.; Jeffers, M.S.; Nguemeni, C.; Shoichet, M.S., Morshead, C.M.; Corbett, D. 2015 “Assessing cognitive function following medial prefrontal stroke in the rat”, Behavioural Brain Research, 294: 102-10

220. Tuladhar, A.; Morshead, C.M.; Shoichet, M.S. 2015 “Circumventing the blood-brain barrier: local delivery of Cyclosporin A stimulates stem cells in stroke-injured rat brain”, J. Controlled Release, 215: 1-11; doi: 1016/j.jconrel.2015.07.023

219. Elliott Donaghue, I.; Shoichet, M.S. 2015 “Controlled release of bioactive PDGF-AA from a hydrogel/nanoparticle composite”, Acta Biomaterialia, 25: 35-42; doi: 10.1016/j.actbio.2015.08.002
(This publication was downloaded 386 times since August 2015)

218. Pakulska, M.M.; Vulic, K.; Tam, R.Y.; Shoichet, M.S. 2015 “Hybrid crosslinked methylcellulose hydrogel: a predictable and tunable platform for local drug delivery”, Advanced Materials 27: 5002-08; doi: 10.1002/adma.201502767

217. Logie, J.; McLaughlin, C.K.; Tam, R.Y., Shoichet, M.S. 2015 “Innovative use of the taxol binding peptide overcomes key challenges of stable and high drug loading in polymeric nanomicelles”, Chemical Communications, 51: 12000-03; doi: 10.1039/C5CC04282H

216. Fuehrmann, T. Obermeyer, J.; Tator, C.H.; Shoichet, M.S. 2015 “Click-crosslinked injectable hyaluronic acid hydrogel is safe and biocompatible in the intrathecal space for ultimate use in regenerative strategies of the injured spinal cord” Methods, 84: 60-69; doi: 10.1016/j.ymeth.2015.03.023

215. Tajdaran, K.; Gordon, T.; Shoichet, M.S.; Borschel, G.H. 2015 “A novel polymeric drug system for localized and sustained release of tacrolimus (FK506)”, Biotechnology and Bioengineering, 112: 1948-53; doi: 10.1002/bit.25598

214. Ballios, B.G.; Cooke, M.J.; Clarke, L.; Cole, B.; Morshead, C.M.; van der Kooy, D.; Shoichet, M.S. 2015 “A hyaluronan based injectable hydrogel improves the survival and integration of stem cell progeny following transplantation” Stem Cell Reports, 4: 1031-45; doi: 10.1016/j.stemcr.2015.04.008 (This publication was downloaded 975 times since May 2015)

213. Elliott Donaghue, I.; Tator, C.H.; Shoichet, MS. 2015 “Sustained delivery of bioactive neurotrophin-3 to the injured spinal cord”, Biomaterials Science, 3: 65-72; doi: 10.1039/c4bm00311j


212. Vulic, K.; Pakulska, M.M.; Sonthalia, R.; Ramchandran, A.; Shoichet, M.S. 2015 “Mathematical model accurately predicts protein release from an affinity-based delivery system”, Journal of Controlled Release, 197: 69-77; doi: 10.1016/j.jconrel.2014.10.032
(This publication was downloaded 957 times between November 2014)

211. Vulic, K.; Shoichet, M.S. 2015 "Affinity-based drug delivery systems for tissue repair and regeneration", Biomacromolecules, 15: 3867-80; doi: 10.1021/bm501084u.

210. Elliott Donaghue, I.; Tam, R.Y.; Sefton, M.V.; Shoichet, M.S. 2014 "Cell and biomolecule delivery for tissue repair and regeneration in the central nervous system", Journal of Controlled Release, 190: 219-27; doi:

209. Witty, A.D.; Mihic, A.; Tam, R.Y.; Fisher, S.A.; Shoichet, M.S.; Li, R.-K.; Kattman, S.J.; Keller, G.M. 2014. “The generation of the epicardial lineage from human pluripotent stem cells”, Nature Biotechnology, 32: 1026-37; doi: 10.1038/nbt.3002

208. Hunt, J.; Sachewky, N.; Cooke, M.J.; Zarin, T.; Mui, C.; Shoichet, M.S.; Morshead, C.M. 2014 “Cyclosporin A enhances neural precursor cell survival through a calcineurin-independent pathway”, Disease Models & Mechanisms, 7: 953-61; doi: 10.1242/dmm.014480

207. Logie, J.; Owen, S.C.; McLaughlin, C.K.; Shoichet, M.S. 2014 “PEG-graft density controls polymeric nanoparticle micelle stability”, Chem Mater, 26: 2847-55;

206. Owen, S.C.; Doak, A.K.; Ganesh, A.N.; Nedyalkova, L.; McLaughlin, C.K.; Shoichet, B.K.; Shoichet, M.S. 2014 “Colloidal drug formulations can explain “bell-shaped” concentration-response curves”, ACS Chemical Biology, 9: 777-84; doi: 10.1021/cb4007584

205. Fisher, S.A.; Tam, R.Y.; Shoichet, M.S. 2014 "Tissue mimetics: engineered hydrogel matrices provide biomimetic environments for cell growth", Tissue Engineering, 20th Anniversary Issue; 20: 1-4; doi: 10.1089/ten.tea.2013.0765

204. McLaughlin, C.K.; Logie, J.; Shoichet, M.S. 2014 "Core and corona modifications for the design of polymeric micelle drug-delivery systems", Israel Journal of Chemistry, 53: 670-79; doi: 10.1002/ijch.201300085


203. Tam, R.; Fuehrmann, T.; Mitrousis, N.; Shoichet, M.S. 2013 "Regenerative therapies for central nervous system disease: a biomaterials approach", Neuropsychopharmacology Reviews, 39: 169-88; doi: 10.1038/npp.2013.237

202. Silva, N.; Moreira, J.; Ribeiro-Samy, S.; Gomes, E.; Tam, R.Y.; Shoichet, M.S.; Reis, R.; Sousa, N.; Salgado, A.J. 2013 “Modulation of bone marrow mesenchymal stem cell secretome by ECM-like hydrogels”, BIOCHIMIE, 95: 2314-19; doi: 10.1016/j.biochi.2013.08.016

201. Owen, S.C.; Patel, N.; Logie, J.; Pan, G.; Persson, H.; Moffat, J.; Sidhu, S.S.; Shoichet, M.S. 2013 “Targeting HER2+ breast cancer cells: lysosomal accumulation of anti-HER2 antibodies is influenced by antibody binding site and conjugation to polymeric nanoparticles”, J Controlled Release, 172: 395-404; doi: 10.1016/j.jconrel.2013.07.011

200. Wang, Y.; Cooke, M.J.; Sachewsky, N; Morshead, C.M.; Shoichet, M.S. 2013 “Bioengineered sequential growth factor delivery stimulates brain tissue regeneration after stroke”, J Controlled Release, 172: 1-11; doi: 10.1016/j.jconrel.2013.07.032
(This publication was downloaded 945 times since August 2013)

199. Chan, D.P.Y.; Deleavey, G.F.; Owen, S.C.; Damha, M.J.; Shoichet, M.S. 2013 “Click conjugated polymeric immuno-nanoparticles for targeted siRNA and antisense oligonucleotide delivery”, Biomaterials, 34: 8408-15; doi: 10.1016/j.biomaterials.2013.07.019
(This publication was downloaded 1370 times since August 2013)

198. Pakulska, M.M.; Vulic, K.; Shoichet M.S. 2013 “Affinity-based release of chondroitinase ABC from a modified methylcellulose hydrogel” J Controlled Release, 171: 11-16; doi: 10.1016/j.jconrel.2013.06.029 (This publication was downloaded 766 times since July 2013)

197. McLean, D.; Cooke, M.J.; Albay, R. 3rd; Glabe, C.G.; Shoichet, M.S. 2013 “PET imaging of fibrillar parenchymal and vascular Amyloid- in TgCRND8 mice”, ACS Chem Neurosci, 4: 613-23; doi: 10.1021/cn300226q

196. Ho, K.S.; Shoichet, M.S. 2013 "Design considerations of polymeric nanoparticle micelles for targeted chemotherapeutic delivery" Current Opinion in Chemical Engineering, 2: 53-59; doi: 10.1016/j.coche.2013.01.003

195. Owen, S.C.; Fisher, S.A.; Tam, R.Y.; Nimmo, C.M.; Shoichet, M.S. 2013 “Hyaluronic acid click hydrogels emulate the extracellular matrix”, Langmuir, 29: 7393-400; doi: 10.1021/la305000w

194. Wood, M.D.; Gordon, T.; Kemp, S.W.P.; Liu, E.H., Kim, H.; Shoichet, M.S.; Borschel, G.H. 2013 “Functional motor recovery is improved due to local placement of GDNF microspheres after delayed nerve repair”, Biotechnology and Bioengineering, 110: 1272-1281; doi: 10.1002/bit.24800

193. Mothe, A.J.; Tam, R.Y.; Zahir, T.; Tator, C.H.; Shoichet, M.S. 2013 “Repair of the injured spinal cord by transplantation of neural stem cells in a hyaluronan-based hydrogel”, Biomaterials, 34: 3775-83; doi: 10.1016/j.biomaterials.2013.02.002

192. Wood, M.D.; Gordon, T.; Kim, H.; Szynkaruk, M.; Phua, P.; Lafontaine, C.; Kemp, S.W.; Shoichet, M.S; Borschel, G.H. 2013 “Fibrin gels containing GDNF microsphers increase axonal regeneration after delayed peripheral nerve repair”, Regenerative Medicine, 8: 27-37; doi: 10.2217/RME.12.105


191. Caicco, M.J.; Cooke, M.J.; Wang, Y.; Tuladhar, A.; Morshead, C.M.; Shoichet, M.S. 2012 “A hydrogel composite system for sustained epi-cortical delivery of Cyclosporin A to the brain for treatment of stroke”, Journal of Controlled Release 166: 197-202

190. Chan, D.P.Y.; Owen, S.C.; Shoichet, M.S. 2012 “Double click: dual functionalized polymeric micelles with antibodies and peptides”, Bioconjugate Chemistry, 24: 105-13

189. Ho, K.S.; Poon, P.C.; Owen, S.C.; Shoichet, M.S. 2012 “Blood vessel hyperpermeability and pathophysiology in human tumour xenograft models of breast cancer: a comparison of ectopic and orthotopic tumours”, BMC Cancer, 12:579

188. McLean D.; Cooke, M.J.; Wang, Y.; Green, D.; Fraser, P.E.; St George-Hyslop, P.; Shoichet, M.S. 2012 “Anti-amyloid--mediated positron emission tomography imaging in Alzheimer’s disease mouse brains”, PLoS One, 7(12): e51958.

187. Caicco, M.J.; Zahir, T.; Mothe, A.J.; Ballios, B.G.; Kihm, A.J.; Tator, C.H.; Shoichet, M.S. 2012 “Characterization of hyaluronan-methylcellulose hydrogels for cell delivery to the injured spinal cord”, J Biomed Mater Res A, 101: 1472-77

186. Tam, R.Y.; Cooke, M.J.; Shoichet, M.S. 2012 “A covalently modified hydrogel blend of hyaluronan-methyl cellulose with peptides and growth factors influences neural stem/progenitor cell fate”, J Materials Chemistry, 22: 19402-11

185. Owen, S.C.; Doak, A.K.; Wassam, P.; Shoichet, M.S.; Shoichet, B.K. 2012 “Colloidal aggregation affects the efficacy of anticancer drugs in cell culture”, ACS Chemical Biology, 7: 1429-35

184. Kang, C.E.; Baumann, M.D.; Tator, C.H.; Shoichet, M.S. 2012 “Localized and sustained delivery of fibroblast growth factor 2 from a nanoparticle-hydrogel composite for treatment of spinal cord injury”, Cells Tissues Organs, 197: 55-63

183. Silva, N.A.; Cooke, M.J.; Tam, R.Y.; Sousa, N.; Salgado, A.J.; Reis, R.L.; Shoichet, M.S. 2012 “The effects of peptide modified gellan gum and olfactory ensheathing glia cells on neural stem/progenitor cell fate”, Biomaterials, 33: 6345-54

182. Wood, M.D.; Kim, H.; Bilbily, A.; Kemp, S.W.P.; Weber, C.; Gordon, T.; Shoichet, M.S., Borschel, G.H. 2012 “GDNF delivered from microspheres enhances peripheral nerve regeneration after delayed nerve repair” Muscle and Nerve, 46: 122-124

181. Guo, X.D.; Zahir, T.; Katayama, Y.; Morshead, C.M.; Shoichet, M.S.; Tator, C.H. 2012 “The effect of growth factors and soluble nogo66 receptor protein on transplanted neural stem/progenitor survival and axonal regeneration after complete transaction of rat spinal cord” Cell Transplantation, 21: 1177-97

180. Stanwick, J.C.; Baumann, M.D.; Shoichet, M.S. 2012 “Enhanced neurotrophin-3 bioactivity and release from a nanoparticle-loaded composite hydrogel”, J Controlled Release, 160: 666-75

179. Aizawa, Y.; Shoichet, M.S. 2012 “The role of endothelial cells in the retinal stem and progenitor cell niche within a 3D engineered hydrogel matrix” Biomaterials, 33: 5198-205

178. Austin, J.W.; Kang, C.E.; Baumann, M.D.; Didiodato, L.; Satkunendrarajah, K.; Wilson, J.R.; Stanisz, G.; Shoichet, M.S.; Fehlings, M.G. 2012 “The effects of intrathecal injection of a hyaluronan-based hydrogel on inflammation, scarring and neurobehavioural outcomes in a rat model of severe spinal cord injury associated with arachnoiditis”, Biomaterials, 33: 4555-64

177. Pakulska, M.M.; Ballios, B.G.; Shoichet, M.S. 2012 "Injectable hydrogels for central nervous system", Biomedical Materials, 7: 024101; doi: 10.1088/1748-6041/7/2/024101 This review paper has been selected as part of the 2012 Highlights of Biomedical Materials.

176. Ballios, B.G.; Clarke, L.; Coles, B.L.K.; Shoichet, M.S.; van der Kooy, D. 2012 “The adult retinal stem cell is a rare cell in the pigmented ciliary epithelium whose progeny can differentiate into photoreceptors”. Biology Open, 1(3): 1-10

175. Stanwick, J.; Baumann, M.D.; Shoichet, M.S. 2012 “In vitro sustained release of bioactive anti-nogoA, a molecule in clinical development for treatment of spinal cord injury”, International Journal of Pharmaceutics, 426: 284-90

174. McLean, D.; Cooke, M.J.; Wang, Y.; Fraser, P.; St. George-Hyslop, P.; Shoichet, M.S. 2012 “Targeting the amyloid–β antibody in the brain tissue of a mouse model of Alzheimer’s disease”, Journal of Controlled Release, 159: 302-08

173. Vulic, K.; Shoichet, M.S. 2012 “Tunable growth factor delivery from injectable hydrogels for tissue engineering”, Journal of the American Chemical Society, 134: 882-85

172. Wang, Y.; Cooke, M.J.; Morshead, C.M.; Shoichet, M.S. 2012 “Hydrogel delivery of erythropoietin to the brain for endogenous stem cell stimulation after stroke injury”, Biomaterials, 33: 2681-92

171. Ho, K.; Aman, A.; Al-awar, R.; Shoichet, M.S. 2012 “Amphiphilic micelles of poly(2-methyl-2-carboxytrimethyle carbonate-co-D,L-lactide)-graft-poly(ethylene glycol) deliver anti-cancer drugs to solid tumours”, Biomaterials, 33: 2223-29

170. Owen, S.C.; Chan, D.P.Y.; Shoichet, M.S. 2012 "Polymeric micelle stability" NanoToday, 7:53-65; doi: 10.1016/j.nantod.2012.01.002


169. Aizawa Y; Owen SC; Shoichet MS. 2011 "Polymers used to influence cell fate in 3-D geometry: new trends" Trends in Polymer Science, 37: 645-58

168. Nimmo, C.M.; Shoichet, M.S. 2011 "Regenerative biomaterials that 'click': simple aqueous-based protocols for hydrogel synthesis, surface immobilization, and 3D patterning" Bioconjug Chem, 22: 2199-209

167. Wylie, R.G.; Ahsan, S.; Aizawa, Y.; Maxwell, K.L.; Morshead, C.M.; Shoichet, M.S. 2011 “Spatially controlled simultaneous patterning of multiple growth factors in three-dimensional hydrogels”, Nature Materials, 10: 799-806

166. Wylie, R.G.; Shoichet, M.S. 2011 “Three-dimensional spatial patterning of proteins in hydrogels” Biomacromolecules, 12: 3789-96

165. Kim, H.; Cooke, M.J.; Shoichet, M.S. 2011 "Creating permissive microenvironments for stem cell transplantation into the central nervous system" Trends in Biotechnology, 30: 55-63

164. Lu, J.; Owen, S.C.; Shoichet, M.S. 2011 “Stability of self-assembled polymeric micelles in serum” Macromolecules, 44: 6002-08(In October 2017, Web of Science ranked this publication at 274 out of 85,683)

163. Kim, H.; Zahir, T.; Tator, C.H.; Shoichet, M.S. 2011 “Effects of dibutyryl cyclic-AMP on survival and neuronal differentiation of neural stem/progenitor cells transplanted into spinal cord injured rats” PLoS ONE, 6(6): e21744, doi: 10.1371/journal.pone.0021744

162. Odedra, D.; Chiu, L.L.Y.; Shoichet, M.S.; Radisic, M. 2011 “Endothelial cells guided by immobilized gradients of vascular endothelial growth factor on porous collagen scaffolds”, Acta Biomaterialia, 7: 3027-35

161. Cooke, M.J.; Wang, Y.; Morshead, C.M.; Shoichet, M.S. 2011 “Controlled epi-cortical delivery of epidermal growth factor for the stimulation of endogenous neural stem cell proliferation in stroke-injured brain” Biomaterials, 32: 5688-97

160. Kim, H.; Tator, C.H.; Shoichet, M.S. 2011 “Chitosan implants in the rat spinal cord: biocompatibility and biodegradation” J Biomed Mater Res A, 97: 395-404

159. Nimmo, C.M.; Owen, S.C.; Shoichet, M.S. 2011 “Diels-alder click crosslinked hyaluronic acid hydrogels for tissue engineering” Biomacromolecules, 12: 824-30
(In October 2017, Web of Science ranked this publication at 335 out of 235,487)

158. Wang, Y.; Cooke, M.J.; Lapitsky, Y.; Wylie, R.G.; Sachewsky, N.; Corbett, N.; Morshead, C.M.; Shoichet, M.S. 2011 “Transport of epidermal growth factor in the stroke-injured brain” J Control Release, 149: 225-35


157. Bozkurt,G.; Mothe, A.J.; Zahir, T.; Kim, H.;Shoichet, M.S.; Tator, C.H. 2010 “Chitosan channels containing spinal cord-derived stem/progenitor cells for repair of subacute spinal cord injury in the rat” Neurosurgery, 67: 1733-44

156. Leipzig ND; Wylie RG; Kim H; Shoichet MS. 2010 “Differentiation of neural stem cells in three-dimensional growth factor-immobilized chitosan hydrogel scaffolds” Biomaterials, 32: 57-64

155. Baker, A.; Kim, H.; Semple, J.; Dumont, D.; Shoichet, M.S.; Tobbia, D.; Johnston, M. 2010 “Experimental assessment of pro-lymphangiogenic growth factors in the treatment of post-surgical lymphedema following lymphadenectomy” Breast Cancer Research, 12: R70

154. Kang, C.E.; Clarkson, R.; Tator, C.H.; Yeung, I.W.T.; Shoichet, M.S. 2010. “Spinal cord blood flow and blood vessel permeability measured by dynamic computed tomography imaging in rats after localized delivery of fibroblast growth factor” J Neurotrauma, 27: 2041-53

153. Aizawa, Y.; Wylie, R.G.; Shoichet, M.S. 2010 “Endothelial cell guidance in 3-D patterned scaffolds” Advanced Materials, 22: 4831-35

152. Nomura, H.; Kim, H.; Mothe, A.; Zahir, T.; Kulbatski, I.; Morshead, C.M.; Shoichet, M.S.; Tator, C.H. 2010 “Endogenous radial glial cells support regenerating axons after spinal cord transection” NeuroReport, 21:871-76

151. Pettikiriarachchi, J.T.S.; Parish, C.L.; Shoichet, M.S.' Forsythe, J.S.; Nisbet, D.R. 2010 "Biomaterials for brain tissue engineering" Australian Journal of Chemistry, 63: 1143-54

150. Cooke, M.J.; Vulic, K.; Shoichet, M.S. 2010 "Design of biomaterials to enhance stem cell survival when transplanted into the damaged central nervous system" Soft Matter, 6: 4988-98 (Invited Review)

149. Owen, S.; Shoichet, M.S. 2010 "Design of three-dimensional biomimetic scaffolds" J Biomed Mater Res A, 94:1321-31 (Invited Review)

148. Rahman, N.; Purpura, K.A.; Wylie, R.G.; Zandstra, P.W.; Shoichet, M.S. 2010. “The use of vascular endothelial growth factor functionalized agarose to guide pluripotent stem cell aggregates toward blood progenitor cells” Biomaterials, 31: 8262-70

147. Baumann, M.D.; Kang, C.E.; Tator, C.H.; Shoichet, M.S. 2010 “Intrathecal delivery of a polymeric nanocomposite hydrogel after spinal cord injury” Biomaterials, 31: 7631-39

146. Yu, L.M.Y.; Miller, F.D.; Shoichet, M.S. 2010 “The use of immobilized neurotrophins to support neuron survival and guide nerve fiber growth in compartmentalized chambers” Biomaterials, 31: 6987-99

145. Lu, J.; Shoichet, M.S. 2010 “Self-assembled polymeric nanoparticles of organocatalytic copoly- merized D,L-lactide and 2-methyl 2-carboxytrimethylene carbonate” Macromolecules, 43: 4943-53

144. Hsieh, A.; Zahir, T.; Lapitsky, Y.; Amsden, B.; Wan, W.; Shoichet, M.S. 2010. “Hydrogel/electrospun fiber composites influence neural stem/progenitor cell fate” Soft Matter; 6: 2227-37

143. Ballios, B.G.; Cooke, M.J.; van der Kooy, D.; Shoichet, M.S. 2010 “A hydrogel-based stem cell delivery system to treat retinal degenerative diseases” Biomaterials; 31: 2555-64

142. Kang, C.E.; Tator, C.H.; Shoichet, M.S. 2010 “Poly(ethylene glycol) modification enhances penetration of fibroblast growth factor 2 to spinal cord tissue from an intrathecal delivery system” J Control Release; 144: 25-31

141. Scanga, V.I.; Goraltchouk, A.; Nussaiba, N.; Shoichet, M.S.; Morshead, C.M. 2010 “Biomaterials for neural tissue engineering: chitosan supports the survival, migration and differentiation of adult-derived neural stem and progenitor cells” Can J Chem, 88: 277-87

140. Leipzig, N.; Xu, C.; Zahir, T.; Shoichet, M.S. 2010 “Functional immobilization of interferon-gamma induces neuronal differentiation of neural stem cells” J Biomed Mater Res A; 93: 625-33

139. Cooke, M.J.; Zahir, T.; Phillips, S.R.; Shah, D.S.H.; Athey, D.; Lakey, J.H.; Shoichet, M.S.; Przyborski, S.A. 2010 “Neural differentiation regulated by biomimetic surfaces presenting motifs of extracellular matrix proteins” J Biomed Mater Res A; 93: 824-32

138. Shoichet, M.S. 2010 "Polymer scaffolds for biomaterials applications" Macromolecules, 43: 581-91